Omics Technologies in Biomarkers Discovery
Biomarkers play a crucial role in diagnosis and treatment of diseases like cancer, and to enable screening of asymptomatic populations. Omics technologies like transcriptomics, genomics and proteomics approaches are increasing the discovery of biomarkers. The techniques like micro array data analysis, computational biology, data mining methods, Transcriptional profiling techniques are used in validating the biomarkers. Genome-wide association studies have helped in understanding the genetic basis of complex diseases and advances in high-throughput technologies. In the research of Biomarkers the Bioinformatics tools help in promoting better diagnosable parameters. There are various applications of bioinformatics in the biomarker research which are obtained by data mining methods and the genomic, proteomic approaches.