Imaging Biomarkers

Imaging biomarkers have a crucial role is new drug development. Drug development has been changed in  last two decades because massive progresses in molecular biology have been made that is  leading to  detailed understanding of the genetic abnormalities in different diseases. The advancements in medical imaging offer the opportunity of using imaging biomarkers to fasten the drug development process.

Imaging Biomarkers can be Anatomical, functional and molecular characterized and these anatomical biomarkers could be the only imaging surrogate endpoints that can be accepted in cancer treatment. Molecular imaging biomarkers  target-specific. Functional imaging biomarkers have the advantage of being downstream markers that probe general capabilities of disease, including cell death, proliferation, glycolysis, tumor invasiveness, angiogenesis, inflammation, fibrosis and they are used as pharmacodynamic biomarkers.

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