Biomarkers research in Immuno-Oncology
is continues to evolve, with offering a new approach to treatment that holds significant promise. If cancer is detected, patients undergo a variety of tests of diagnosis, prognosis, and treatment decision-making. The need for multiple, diverse diagnostic approaches to guide treatment decision-making in oncology is not likely to change, and the emergence of groundbreaking that work by stimulating the immune system to attack a is only adding to the diagnostic complexity. Biomarker-based CDx are essential to guide treatment decisions and are a valuable tool to aid in patient selection for clinical testing of new I/O drugs.
Tissue-based biomarkers are proving to be invaluable for helping to stratify patients based on the immune context of a and the patient-specific characteristics of the tumour microenvironment as well as interactions between tumour and immune cells and between a tumour and surrounding tissues. Tissue context can capture this diversity and complexity, and biomarker-based CDx can drive individualized treatment decisions.