Biomarkers in Genomics

Recent research of Biotechnology and Genomics signifies the advancement of biomarkers to detect individual disease risk and enhance diagnostic classification to better inform personalized treatment. The identification and development of  biomarkers for personalized, preventive and predictive medicine was a major impulse of Human Genome Project.

Biomarkers related to Genomics measure changes in the quantity or nature of nucleic acids . DNA-based biomarkers include copy number variation, mutations (including polymorphisms, somatic mutations, and other genetic variants), and epigenetic modifications. RNA expression-based biomarkers include quantification of mRNA, microRNA and long noncoding RNA expression.

·         Nucleic acid Biomarkers

·         RNA Expression profiling

·         DNA Sequencing

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